DOCUMENTATION OF WEB APPLICATION

Screenshot explanation with radio-number marked picture:

Explanation of the radio-marked points:

[1] Selection menu for browsing the pages of the web-server. [2] Peptide/protein submission block for generation of pR value. [3] Submission of virus and protein name for rendering graph in the output box. [4] Protein segment variability curve in blue (9aa stretch) & it's axis values are indicated on right side Y-axis. [5] Predicted and scaled B-Cell epitopic property score (for peptide stretch 9aa) in pink line. [6] Predicted and scaled T-Cell epitopic property score (for peptide stretch, 9aa) in cyan line. [7] Predited and scaled relative solvent accessibility for peptide stretch (9aa). [8] Predicted top-20 co-evolving residues marked as black column.

Details of the sequence database:

Organism Name Protein Name Number of Sequences Reference Sequence ID Database Details
SARS CoV 2 Surface Glycoprotein S 20173 YP_009724390 NCBI Virus Database [link]
SARS CoV 2 Envelope Protein 20313 YP_009724392 NCBI Virus Database [link]
SARS CoV 2 Membrane Glycoprotein M 20245 YP_009724393 NCBI Virus Database [link]
SARS CoV 2 ORF3a Protein 20342 YP_009724391 NCBI Virus Database [link]
SARS CoV 2 ORF8 Protein 20237 YP_009724396 NCBI Virus Database [link]
H5N1 Neuraminidase Protein 2943 YP_308668 NCBI Virus Database [link]
H5N1 Hemagglutinin Protein 3669 YP_308669 NCBI Virus Database [link]
H5N1 Matrix Protein M1 3054 YP_308671 NCBI Virus Database [link]
H5N1 Matrix Protein M2 2430 YP_308670 NCBI Virus Database [link]
H1N1 Neuraminidase Protein 23179 NP_040981 NCBI Virus Database [link]
H1N1 Hemagglutinin Protein 22901 NP_040980 NCBI Virus Database [link]
H1N1 Matrix Protein M1 18429 NP_040978 NCBI Virus Database [link]
H1N1 Matrix Protein M2 18088 NP_040979 NCBI Virus Database [link]
H2N2 Neuraminidase Protein 235 YP_308872 NCBI Virus Database [link]
H2N2 Hemagglutinin Protein 204 YP_308850 NCBI Virus Database [link]
H2N2 Matrix Protein M1 226 YP_308854 NCBI Virus Database [link]
H2N2 Matrix Protein M2 229 YP_308853 NCBI Virus Database [link]
H3N2 Neuraminidase Protein 19307 YP_308842 NCBI Virus Database [link]
H3N2 Hemagglutinin Protein 22919 YP_308839 NCBI Virus Database [link]
H3N2 Matrix Protein M1 19486 YP_308841 NCBI Virus Database [link]
H3N2 Matrix Protein M1 18983 YP_308840 NCBI Virus Database [link]
MERS Surface Glycoprotein S 832 YP_009047204 NCBI Virus Database [link]
MERS Envelope Protein E 706 YP_009047209 NCBI Virus Database [link]
MERS Membrane Glycoprotein M 697 YP_009047210 NCBI Virus Database [link]
SARS Surface Glycoprotein S 103472 YP_009724390 NCBI Virus Database [link]
SARS Envelope Protein E 145473 YP_009724392 NCBI Virus Database [link]
SARS Membrane Glycoprotein M 143694 YP_009724393 NCBI Virus Database [link]
SARS Protein ORF3a 273952 YP_009724391 NCBI Virus Database [link]
SARS Protein ORF8 243404 YP_009724396 NCBI Virus Database [link]